Systems Biology Centre   IPCR  Research Interests   Teaching   Job vacancies   Grants  Publications    Applied Maths page

Nigel Burroughs

Professor in Systems Biology,
Mathematics Institute and Warwick Systems Biology Centre,
University of Warwick, Coventry. CV4 7AL. UK.

Tel: 024 76524682. Email: N.J.Burroughs @


Photos: one of my stone sculptures and the making a gorilla bronze in Aberdeen.

I also have a website at Warwick Systems Biology with publications, and more accessible content for the general public.

Research interests

My main research interests are mathematical and statistical applications in cellular biology and systems biology, being motivated by both theoretical issues and problems in the analysis of biological data (fluorescence data and high throughput data). For instance, spatial information is often hard to extract from gfp images but can be very informative for modelling, while high through-put data (gene expression, proteomics, metabolomic data) remain highly challenging despite a decade of research. I use a variety of modelling and data analysis methods, including Modelling: dynamical systems, partial differential equations, stochastic models (eg random walks, queueing theory), large deviation methods, Statistical computation analysis methods: Bayesian methods such as Markov chain Monte Carlo techniques, including model comparison and selection methods.
My main projects at present are in immunology (NK synapse, T cell signalling), cell biology (microtubules), inference of regulatory gene-protein networks using a variety of data sources (data integration) and development of algorithms for analysis of biological experiments (gfp data, FRAP).

immunology, cellular biology, gene networks, Bee project, Nodulation project, photosynthesis project


I teaching a course in the new in the Warwick Systems Biology doctoral training centre, Modelling and statistics in Systems Biology.
Previously I have taught in the Mathematics degree programmes- Probability Theory in Bioinformatics, a 3rd year course covering dynamic programming, graph theory and Markov chains, Topics in Mathematical Biology, MA390, a third year course that is essentially a course on waves and stability analysis in biology, Mathematics in Medicine, MA498, a fourth year course on mathematical immunology and virology which I designed in 2000, and Variational principles, a second year course.

Postdocs and Jobs

Three PDRA positions are currenly available:

Research Fellow in Statistical analysis of honeybee viral immunity under mite infestation. Job advert link, job number 70471-031. Closes April 15th.

Research Fellow in Inference of the root nodulation gene regulatory network in legumes. Job advert link, number 71022-031. Closes April 15th.

Mathematical modelling of CO2 delivery and photosynthesis efficiency of the chloroplast. Job advert link, number 71023-031. Closes 15th April.

Also look at the Warwick Systems Biology web site, there may be opportunities there.

Currently I have 1 PDRA, 3 open PDRA posts (above) and 4 PhD students-

Research Programmes/Initiatives.

In early 2006 the Warwick Systems Biology center was established bringing together expertise in mathematics, statistics, biology and statistics. It has cell regulation as its major theme with emphasis on data analysis methodology, (neuro)physiology, plant science and signalling. In Oct 2007, a Systems Biology DTC was launched (BBSRC funded).

A major Interdisciplinary Programme in Cellular regulation was launched in Oct 03 focussing on regulatory issues of cells at the genetic and cytosol levels. I am the programme manager responsible for the coordination and cohesion of the research program. An interdisciplinary post graduate training program, MOAC, also started in Oct 03.

We are always keen to expand our team, so contact me if you are interested in joining us. Systems Biology is a rapidly growing field with funding opportunities from EPSRC, BBSRC, PPARC, the Leverhulme Trust, the EU and the Wellcome Trust. I made the transition myself from Physics into Biological applications while on an EPSRC Advanced Fellowship (B/94/AF/1822).


My research is funded from EPSRC, BBSRC and the Leverhulme Trust as follows

Previous grants have included:

Top   Research Interests   Teaching   The Group   Grants  Jobs  Publications  Applied Maths page

March 2011.