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Curriculum vitae | Publications | MSc/PhD Research projects

Yep! That's me!

Hugo van den Berg

Address
Warwick Systems Biology Centre (at Coventry House), University of Warwick, Coventry CV4 7AL, United Kingdom.
Phone
+44 (0)2476 523698
Fax
+44 02476 524182
E-mail
hugo@maths.warwick.ac.uk

Information and resources for prospective and current students

Our interdisciplinary master's courses  are open to students from the natural sciences and mathematics. A good degree in any one of those is all you need, since the course includes primers on chemistry, biology, mathematics and statistics. You can prepare yourself optimally for these fast-paced primers by brushing up on some of these subjects; check out the list of recommended textbooks.
Mathematics worksheets  suitable for self-study are also available.
Find out if you are eligible for a fully-funded studentship. Choose the doctoral training course that is right for you.
Lecture notes for An Introduction to Mathematical Biology
Collected worksheets Mathematics for Multidisciplinary Masters
A brief description of Topics in Mathematical Biology
A selection of MSc/PhD research project topics

Current Research

Immunology
Quantitative theories of T cell responsiveness (preprint). Present research is aimed at elucidating the relationships between immune response efficacy and the statistical distributions of T cell specificities among the naive repertoire and among T cell populations which respond to given antigenic challenges. At the heart of the theory is a model of T cell receptor triggering kinetics, which relates T cell specificity to the distribution of antigenic peptide-presenting MHC molecules on the conjugate cell. This kinetic model allows us to describe how measures for T cell specificity functionally depend upon MHC-presentation levels. An example of such a specificity measure is the fraction of naive T cell clonotypes that will respond to a given antigen; another example is the rate at which cytolytic effector cells destroy target cells. Such specificity measures (as well as their distributions) underly the dynamics of T cell activation and of the ensuing effector response, which in turn determine response efficacy. The ultimate goal of this programme is to link immune efficacy in a quantitative manner MHC/antigen presentation levels on antigen-presenting cells.

Endocrine control of macrochemical dynamics
Click here for a brief discussion.







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